发表论文

2024年

 

  1. Shuhao Feng, Zihang Feng, Yiran Wei, Hongfang Li, Zhonghao Deng, Zheting Liao, Liang Zhao. EEF1B2 regulates bone marrow-derived mesenchymal stem cells bone-fat balance via Wnt/β-catenin signaling. Cellular and Molecular Life Sciences. 2024. on press.
  2. Zheting Liao, Xiaoyong Zheng, Hongfang Li, Zhonghao Deng, Shuhao Feng, Hongbo Tan, Liang Zhao. Carboxypeptidase M modulates BMSCs osteogenesis-adipogenesis via the MAPK/ERK pathway: An integrated single-cell and bulk transcriptomic study. The FASEB Journal. 2024. on press.
  3. 戎圣炜, 李宏芳,魏怡然,冯子航,邓仲豪,赵亮. 锌指蛋白-36缺陷抑制小鼠的成骨细胞分化:基于激活ERK/MAPK通路. 南方医科大学学报. 2024, 44(4): 697-705

2023年

 

  1. Deng Zhonghao, Rong Shengwei, Gan Lu, Wang Fuhua, Bao Liangxiao, Cai Fang, Liao Zheting, Jin Yu, Feng Shuhao, Feng Zihang, Wei Yiran, Chen Ruge, Jin Yangchen, Zhou Yanli, Zheng Xiaoyong, Huang Liping, Liang Zhao(corresponding author). Temporal transcriptome features identify early skeletal commitment during human epiphysis development at single-cell resolution. iScience. 2023 Jun 24;26(8):107200.(二区)link
  2. Gan Lu, Deng Zhonghao, Wei Yiran, Li Hongfan, Liang Zhao(corresponding author). Decreased expression of GEM in osteoarthritis cartilage regulates chondrogenic differentiation via Wnt/β-catenin signaling. J Orthop Surg Res. 2023 Oct 4;18(1):751.(三区)link

2022年

 

  1. Zheting Liao, Yu Jin, Yuhao Chu, Hansen Wu, Xiaoyu Li, Zhonghao Deng, Shuhao Feng, Nachun Chen, Ziheng Luo, Xiaoyong Zheng, Liangxiao Bao, Yongqing Xu, Hongbo Tan, Liang Zhao(corresponding author),. Single-cell transcriptome analysis reveals aberrant stromal cells and heterogeneous endothelial cells in alcohol-induced osteonecrosis of the femoral head. Commun Biol 5, 324 (2022).(IF 6.268)link to

2021年

 

  1. Qiu G, Wu H, Huang M, Ma T, Schneider A, Oates TW, Weir MD, Xu HHK, Zhao Liang(corresponding author): Novel calcium phosphate cement with biofilm-inhibition and platelet lysate delivery to enhance osteogenesis of encapsulated human periodontal ligament stem cells.Materials Science and Engineering: C, 2021, 128:112306.(IF 7.328)link to
  2. Qiu G, Huang M, Liu J, Wang P, Schneider A, Ren K, Oates TW, Weir MD, Xu HHK, Zhao Liang(corresponding author). Antibacterial calcium phosphate cement with human periodontal ligament stem cell-microbeads to enhance bone regeneration and combat infection. J Tissue Eng Regen Med. 2021 Mar;15(3):232-243. (IF:3.963) link to
  3. Xiaoyu Li, Zheting Liao, Zhonghao Deng, Nachun Chen, Liang Zhao(responding author), Combining bulk and single-cell RNA-sequencing data to reveal gene expression pattern of chondrocytes in the osteoarthritic knee, Bioengineered, 2021, 12(1): 997-1007.
  4. Yingzhi Gu, Xianju Xie, Rui Zhuang, Michael D. Weir, Thomas W. Oates, Yuxing Bai, Zhao Liang(corresponding author), Hockin H.K. Xu, A Biphasic Calcium Phosphate Cement Enhances Dentin Regeneration by Dental Pulp Stem Cells and Promotes Macrophages M2 Phenotype In Vitro, Tissue Engineering: Part A.2021.link to the Journal

2020年

 

  1. Bing SONG, Haijun FU, Jianwei LIU, Ke REN, Michael D. WEIR, Abraham SCHNEIDER, Ping WANG, Yang SONG, Liang ZHAO and Huakun XU. c. c. Aug.2020(IF:1.359) link to the Journal
  2. Taifeng Zhou, Yi Fan, Yifan Liu, Shuhao Feng, Qian Cong, Yaxing Zhou, Jiachen Lin, Liang Zhao, Yingzi Yang. Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin. eLife. 2020 Mar 18;9. pii: e52779. doi: 10.7554/eLife.52779(IF:7.551) link to
  3. Xianling Gao, Wei Qin, Lingling Chen, Wenguo Fan, Tao Ma, Abraham Schneider, Mengyao Yang, Obinna N. Obianom, Jiayao Chen, Michael D. Weir, Yan Shu, Liang Zhao(co-corresponding author), Zhengmei Lin, Hockin H. K. Xu. Effects of targeted delivery of metformin and dental pulp stem cells on osteogenesis via demineralized dentin matrix under high glucose conditions. ACS Biomaterials Science & Engineering, Publication Date: March 17, 2020. DOI: 10.1021/acsbiomaterials.0c00124. IF:4.511)link to
  4. Shizhou Wu, lei Lei, Hui Zhang, Jin Liu, Michael D. Weir, Abraham Schnerider, Zhao Liang(corresponding author), Jun Liu, Hockin H.K. Xu, Nanographene oxide-calcium phosphate to inhibit Staphylococcus aureus infection and support stem cells for bone tissue engineering, Journal of Tissue Engineering and Regenerative Medicine, 2020, 14(12): 1779-91.
  5. Li G, Shen W, Zhao Liang, Wang T, Pan Z, Sheng S, Xu W. Combined construction of injectable tissue-engineered bone with CPC and BMMSCs and its study of repair effect on rabbit bone defect model. J Musculoskelet Neuronal Interact. 2020 Mar 3;20(1):142-148.
  6. 冯舒皓, 包良笑, 邱耿涛, 廖哲霆, 邓仲豪, 陈纳淳, 楚玉豪, 骆梓恒, 金昱, 李啸宇, 杨英姿, 赵亮(通讯作者), 银染法和鬼笔环肽染色观察不同发育阶段小鼠骨细胞突触[J], 南方医科大学学报, 2020, 40(11): 1656-1661.

2019年

 

  1. Jin Liu, Zeqing Zhao, Jianping Ruan, Michael D. Weir, Tao Ma, Ke Ren, Abraham Schneider, Thomas W. Oates, Ang Li, Liang Zhao*(co-corresponding author),, Hockin H.K. Xu,Stem cells in the periodontal ligament differentiated into osteogenic, fibrogenic and cementogenic lineages for the regeneration of the periodontal complex,Journal of Dentistry,Volume 92,2020,(IF:3.28) link to
  2. Nakano, S., Inoue, K., Xu, C., Zhonghao Deng., Syrovatkina, V., Vitone, G., Liang Zhao., Huang, X. Y., Zhao, B. (2019). G-protein Gα13 functions as a cytoskeletal and mitochondrial regulator to restrain osteoclast function. Scientific reports, 9(1), 4236. (IF=4.122)
  3. 邓仲豪,林锦德,吴德胜,陈宇璠,廖哲霆,冯舒皓,陈纳淳,赵宝红,赵亮.小鼠胫骨不脱钙树脂包埋法的改良与应用研究.南方医科大学学报,2019,9期

2018年

 

  1. Yang Xia, Jianfei Sun, Zhao Liang, Feimin Zhang, Xing-Jie Liang, Yu Guo, Michael D. Weir, Mark A. Reynolds, Ning Gu, Hockin H. K. Xu. Magnetic field and nano-scaffolds with stem cells to enhance bone regeneration. Biomaterials . (Accepted August. 2018)(IF:8.806)
  2. 宋兵, 廖哲霆, 邓仲豪, 吴德胜, 冯舒皓, 赵亮(通讯作者).磷酸钙/壳聚糖/小分子腺苷复合材料修复大鼠颅骨极限骨缺损.南方医科大学学报, 2018, 16(3): 716.
  3. 廖哲霆,邢祯全,陈宇璠,邓仲豪,吴德胜,赵亮(通讯作者).关节腔注射抗坏血酸/氯化铁可延缓骨性关节炎大鼠软骨退变. 南方医科大学学报, 2018, 38(1): 62-68.
  4. Inoue, K., Zhonghao Deng., Chen, Y., Giannopoulou, E., Xu, R., Gong, S., Greenblatt, M. B., Mangala, L. S., Lopez-Berestein, G., Kirsch, D. G., Sood, A. K., Liang Zhao., Zhao, B. (2018). Bone protection by inhibition of microRNA-182. Nature communications, 9(1), 4108. (IF=12.353)

2017年

 

  1. Wei Qin, Qi-Ting Huang, Michael D. Weir, Zhi Song,Ashraf F. Fouad, Zheng-Mei Lin, Liang Zhao(co-corresponding author), Hockin H. K. Xu. Alcohol Inhibits Odontogenic Differentiation of Human Dental Pulp Cells by Activating mTOR Signaling. Stem Cells International. (accepted,July 2017) (IF:3.54)
  2. Ping Wang, Lin Wang, Chongyun Bao, Qianming Chen, Michael D. Weir, Laurence C. Chow4, Liang Zhao(co-corresponding author), Xuedong Zhou, Hockin H. K. Xu, Mark A. Reynolds. A new generation of calcium phosphate cement constructs with stem cells and biologics for bone tissue engineering. Bone Research (Invited review article, 2017) (IF:9.326)
  3. Chi Zhang, Kevin Hu, Xian Liu, Mark A. Reynolds, Chongyun Bao, Ping Wang, Liang Zhao*(co-corresponding author), Hockin H.K. Xu, Novel hiPSC-based tri-culture for pre-vascularization of calcium phosphate scaffold to enhance bone and vessel formation. Materials Science and Engineering: C. (Accepted Apl. 2017)
  4. Gengtao Qiu, Ping Wang, Jinyu Sun, Yang Song, Guangjun Li, Hockin H. K. Xu*, Zhao Liang*(co-corresponding author). Bone regeneration in minipigs via calcium phosphate cement scaffold delivering autologous BMSCs and platelet-rich plasma. J Tissue Engineering and Regenerative Medicine. 2017.18. doi: 10.1002/term.2416. [Epub ahead of print]
  5. Wenchuan Chen, Xian Liu, Qianmin Chen, Chongyun Bao, Zhao Liang*(co-corresponding author), Zhimin Zhu, Hockin H.K. Xu*. Angiogenic and osteogenic regeneration in rats via calcium phosphate scaffold and endothelial cell coculture with hBMSCs, hUCMSCs, hiPSC-MSCs and hESC-MSCs. J Tissue Engineering and Regenerative Medicine. 2017 Jan 18. doi: 10.1002/term.2395. [Epub ahead of print]
  6. Xian Liu, Wenchuan Chen, Chi Zhang, Wahwah Thein-Han, Kevin Hu, Mark A. Reynolds, Chunyun Bao, Ping Wang, Zhao Liang*(co-corresponding author),  Hockin H. K. Xu*. Co-seeding human endothelial cells with hiPSC-derived mesenchymal stem cells on calcium phosphate scaffold enhances osteogenesis and vascularization in rats. Tissue Engineering Part A. February 2017, ahead of print. doi:10.1089/ten.TEA.2016.0485.
  7. Yang Song, Chi Zhang, Ping Wang, Lin Wang, Chunyun Bao,Michael D. Weir, Mark A. Reynolds, Ren Ke, Zhao Liang*(co-corresponding author), Hockin H. K. Xu*. Engineering bone regeneration with novel cell-laden hydrogel microfiber-injectable calcium phosphate scaffold. Materials Science & Engineering C-Materials for Biological Applications. (Accepted Feb. 2017)

2016年

 

  1. Lin Wang, Xianju Xie, Michael D. Weir, Ashraf F. Fouad, Zhao Liang*(co-corresponding author), Hockin H. K. Xu*. Effect of bioactive dental adhesive on periodontal and endodontic pathogens. Journal of Materials Science: Materials in Medicine.  2016.27(11):168.
  2. 7. Gengtao Qiu, Ping Wang, Guangjun Li,Zhanjun Shi, Michael D. Weir,Jinyu Sun, Yang Song, Jixing Wang, Huakun H. Xu*, Zhao Liang*(co-corresponding author).Minipig-BMSCs combined with a self-setting calcium phosphate paste for bone tissue engineering. Mol Cell Biochem. 2016.58(11):748-756.
  3. 8. Wang Lin, Wang Ping, Weir Michael, Reynolds Mark, Zhao Liang*(co-corresponding author), Huakun H. Xu*. Hydrogel fibers encapsulating hiPSC-MSCs, hESC-MSCs and hUCMSCs in injectable calcium phosphate scaffold for bone tissue engineering.  Biomedical Materials. 2016.11(6):065008.(journal's Highlights)
  4. Lin Wang, Chi Zhang, Chunyan Li, Michael D. Weir, Ping Wang, Mark A. Reynolds, Zhao Liang*(co-corresponding author), Hockin H.K. Xu. Injectable calcium phosphate with hydrogel fibers encapsulating induced pluripotent, dental pulp and bone marrow stem cells for bone repair. Materials Science and Engineering:C. 69:1125-1136(2016).
  5. Ping Wang, Yang Song, Michael D. Weir, Jinyu Sun, Zhao Liang*(co-corresponding author), Carl G. Simon, Hockin Xu. A self-setting  iPSMSC-alginate-calcium phosphate paste for bone tissue engineering. Dental Materials.  32(2):252-63(2016).

2015年

 

  1. Wang Ping, Liu Xian, Zhao Liang*(co-corresponding author), Michael Weir, Sun Jirun, Chen Wenchuan, Man Yi, Xu Huakun*. Bone tissue engineering via human induced pluripotent, umbilical cord and bone marrow mesenchymal stem cells in rat cranium. Acta  Biomaterialia. 18:236-48(2015).
  2. Shi Zhe, Zhao Liang*(co-corresponding author), Qiu Gengtao, He Ruixuan, Michael S. Detamore*. The effect of extended passaging on the phenotype and osteogenic potential of human umbilical cord mesenchymal stem cells. Mol Cell Biochem. 401:155–164,(2015).

2014年

 

  1. P Wang, Zhao, L, W Chen, X. Liu, MD Weir, HHK Xu. Stem Cells and Calcium Phosphate Cement Scaffolds for Bone Regeneration. J Dent Res, 2014.(Epub ahead)
  2. Wang Ping, Zhao Liang*(co-corresponding author), Liu Jason, Michael D Weir, Xuedong Zhou*, Xu Huakun*. Bone tissue engineering via nanostructured calcium phosphate biomaterials and stem cells. Bone Research.2:1-13(2014).

2012年

 

  1. Dormer N, Singh M, Zhao L, Detamore MS. Osteochondral interface regeneration of the rabbit knee with macroscopic gradients of bioactive signals. Journal of Biomedical Materials Research: Part A.100(1):162-70,2012.

2011年

 

  1. Wang, L, Liang Zhao, Michael S. Detamore. Human umbilical cord mesenchymal stromal cells in a sandwich approach for osteochondral. tissue engineering. J Tissue Eng Regen Med. 5(9): 712-721(2011).
  2. Zhao, L, M Tang, MD Weir, MS Detamore, HHK Xu. Osteogenic media and rhBMP-2-induced differentiation of umbilical cord mesenchymal stem cells encapsulated in alginate microbeads and integrated in an injectable calcium phosphate-chitosan fibrous scaffold. Tissue Eng Part A. 17(7-8): 969-979(2011).

2010年

 

  1. Zhao, L. and M. S. Detamore. Chondrogenic differentiation of stem cells in human umbilical cord stroma with PGA and PLLA scaffolds. J Biomed Sci Eng. 3(11): 1041-1049(2010).
  2. Xu, H.H, M.S, Liang Zhao. Umbilical cord stem cell seeding on fast-resorbable calcium phosphate bone cement. Tissue Eng Part A. 16(9): 2743-2753 (2010).
  3. Xu, H. H, L. Zhao, M.D. Weir. Stem cell-calcium phosphate constructs for bone engineering. J Dent Res. 89(12): 1482-1488(2010).
  4. Zhao, L, Burguera EF, Xu Huakun, Amin N, Ryou H, Arola DD. Fatigue and human umbilical cord stem cell seeding characteristics of calcium phosphate-chitosan-biodegradable fiber scaffolds. Biomaterials. 31(5): 840-847(2010).
  5. Zhao, L, Weir MD(co-first author), Xu Huakun. An injectable calcium phosphate-alginate hydrogel-umbilical cord mesenchymal stem cell paste for bone tissue engineering. Biomaterials. 31(25): 6502-6510(2010).
  6. Zhao, L, Weir MD, Xu Huakun. Human umbilical cord stem cell encapsulation in calcium phosphate scaffolds for bone engineering. Biomaterials. 31(14): 3848-3857(2010).

赵亮教授

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南方医科大学南方医院

 

广东省广州市白云区广州大道北1838号南方医院新外科楼16楼关节与骨病外科

邮编:510515

南方医科大学南方医院临床研究中心

 

广东省广州市白云区广州大道北1838号南方医院新实验楼7楼关节与骨病外科

邮编:510515

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